Comparison of receptor affinity of natSc-DOTA-TATE versus natGa-DOTA-TATE
نویسندگان
چکیده
منابع مشابه
Comparison of receptor affinity of natSc-DOTA-TATE versus natGa-DOTA-TATE.
BACKGROUND 44Sc as a positron emitter can be an interesting alternative to 68Ga (T½=67.71 min) due to its longer half-life (T½=3.97 h). Moreover, the b-emitter 47Sc can be used for therapy when attached to the same biomolecule vectors. DOTA as a chelating agent has been proven suitable for the radiolabelling of peptides recognising tumour cell receptors in vivo with M3+ radiometals. DOTA-deriva...
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Peptide-receptor imaging and therapy with radiolabeled somatostatin analogs such as 68Ga-DOTA-TATE and 177Lu-DOTA-TATE have become an effective treatment option for SSTR-positive neuroendocrine tumors. The purpose of this study was to evaluate the correlation of somatostatin receptor-2 (SSTR2) expression with 68Ga-DOTA-TATE uptake and 177Lu-DOTA-TATE therapy in neuroblastoma (NB) xenograft mode...
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A 65-year-old female patient who had been operated 20 years ago for parathyroid adenoma presented with left arm mass suspicious for metastatic lesion. First she was referred for bone scintigraphy for evaluation of osteoblastic activity of this lesion and examining other possible lesions at the skeleton. 99mTcMDP whole-body bone scan revealed multiple increased tracer uptake at the skeletal syst...
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We explain a technical result about p-adic cohomology and apply it to the study of Shimura varieties. The technical result applies to algebraic varieties with torsion-free cohomology, but for simplicity we only treat abelian varieties.
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ژورنال
عنوان ژورنال: Nuclear Medicine Review
سال: 2011
ISSN: 1506-9680
DOI: 10.5603/nmr.2011.00021